Patients with recurring depression tend to focus on negative

Major depression ranks among the prevalent mental health disorders in the United States. As per the data released by the National Institute of Mental Health, in the year 2020, about 21 million American adults, constituting 8.4% of the population, reported experiencing at least one episode of major depression. This condition is characterized by a persistent period of at least two weeks marked by a low mood or a loss of interest and pleasure in everyday activities, which can significantly disrupt a person's ability to engage in essential life functions.

Despite the availability of established treatments for depression, the recurrence rates for major depressive disorder remain alarmingly high. More than 50% of individuals who experience a first-time episode of major depression will encounter subsequent episodes, often relapsing within two years of their initial recovery. Consequently, there is a pressing need to delve deeper into the risk factors associated with major depressive disorder in order to enhance treatment strategies and prevent relapse.

In a recent study, researchers undertook a comprehensive meta-analysis that scrutinized 44 studies encompassing 2081 participants with a history of major depressive disorder and 2285 individuals who were deemed healthy controls. These studies primarily focused on participants' response times to stimuli of various emotional valences, including negative, positive, or neutral. In certain instances, participants were presented with images of happy, sad, or neutral human faces and were instructed to respond by pressing distinct buttons corresponding to each emotion. In other cases, participants were tasked with reacting to positive, negative, or neutral words.

The collective results of these studies indicated that, on the whole, healthy participants exhibited quicker responses to both emotional and non-emotional stimuli compared to participants with a history of depression, irrespective of whether the stimuli carried positive, neutral, or negative emotional weight. However, individuals who had previously grappled with major depressive disorder dedicated more time to processing negative emotional stimuli as opposed to positive stimuli when compared to the control group.

It was observed that while healthy controls displayed a noteworthy difference in the time they allocated to processing positive versus negative emotional stimuli in comparison to those in remission from major depression, such distinctions did not emerge when examining the time allocated to processing negative versus neutral stimuli or positive versus neutral stimuli.

The overarching implication of these findings is that individuals who have experienced recurrent episodes of major depressive disorder not only exhibit a reduced ability to regulate the information they process compared to their healthy counterparts, but they also display a heightened inclination toward focusing on negative information over positive or neutral information, as noted by Wen, the lead researcher.

In light of these discoveries, Wen suggests that these findings have vital implications for the treatment of depression. Merely targeting the reduction of processing negative information may prove insufficient in the prevention of depression relapse. Instead, it may be beneficial for patients to adopt strategies aimed at augmenting the processing of positive information, offering a more holistic approach to managing and preventing this challenging mental health condition.

Read the study results on ScienceDaily 


How Talk Therapy Can Help

Dr. Jenny Holland, PsyD -- Dr. Holland specializes in working with individuals with depression and/or anxiety, those who have experienced trauma, chronic illnesses or conditions associated with aging as well as identity issues.

Talk therapy, also known as psychotherapy or counseling, plays a pivotal role in helping patients with recurring depression regain control over their lives and find lasting relief from the debilitating grip of this mental health condition. One of the primary benefits of talk therapy lies in its ability to provide individuals with a safe and empathetic space to express their thoughts, emotions, and concerns. For those experiencing recurring depression, this opportunity to openly share their experiences can be incredibly liberating. We help patients explore the underlying causes of their depression, often uncovering deep-seated issues or past traumas that may be contributing to their recurring episodes. Through this process of self-discovery, patients can develop a clearer understanding of their triggers and thought patterns, empowering them to develop healthier coping mechanisms and resilience against future depressive episodes.

Furthermore, talk therapy equips individuals with practical tools and strategies to manage their depression effectively. Cognitive-behavioral therapy (CBT), for instance, is a widely used approach that helps patients identify and challenge negative thought patterns and replace them with more constructive thinking. This process enables individuals to break the cycle of recurring depressive episodes by altering their perceptions and behaviors. Additionally, interpersonal therapy (IPT) can assist patients in improving their interpersonal relationships and communication skills, which can be critical in mitigating some of the social factors that contribute to depression recurrence. In essence, talk therapy not only provides emotional support but also empowers individuals with the skills and insights needed to navigate the challenges posed by recurring depression and lead fulfilling lives.

Dr. Holland will tailor treatment to meet your specific needs. Fill out the online appointment form to reserve an appointment or call 707-479-2946.